USC-OGP 2-DE database Two-dimensional polyacrylamide gel electrophoresis database

USC-OGP 2-DE database  Search by                Maps             Select Remote Interfaces [All Interfaces] SWISS-2DPAGE World-2DPAGE Portal World-2DPAGE Repository Exclude local DBs has only effect if a remote interface is selected

Searching in 'USC-OGP 2-DE database' for entry matching: TPM4_HUMAN USC-OGP 2-DE database:  TPM4_HUMAN TPM4_HUMAN General information about the entry View entry in simple text format Entry name TPM4_HUMAN Primary accession number P67936 Secondary accession number(s) P07226 integrated into USC-OGP 2-DE database on  January 17, 2017 (release 1) 2D Annotations were last modified on January 17, 2017 (version 1) General Annotations were last modified on  April 5, 2017 (version 2) Name and origin of the protein Description RecName: Full=Tropomyosin alpha-4 chain; AltName: Full=TM30p1; AltName: Full=Tropomyosin-4;. Gene name Name=TPM4 Annotated species Homo sapiens (Human) [TaxID: 9606] Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. References [1]   2D GEL CHARACTERIZATION Author 1., Author 2. Submitted (Mar-2011) to Current 2D PAGE maps for identified proteins How to interpret a protein PLATELET_4-5 {PLATELET 4-5} Homo sapiens (Human)   map experimental info   PLATELET_4-5 MAP LOCATIONS: SPOT OGP-0112: pI=4.67; Mw=37930 SPOT OGP-0138: pI=4.65; Mw=32668 SPOT OGP-0161: pI=4.69; Mw=29612 PLATELET_6-11 {PLATELET 6-11} Homo sapiens (Human)   map experimental info   PLATELET_6-11 MAP LOCATIONS: SPOT OGP-0994: pI=10.61; Mw=28007 UVEAL_MELANOMA_3-10 {UVEAL MELANOMA 3-10} Homo sapiens (Human)   map experimental info   UVEAL_MELANOMA_3-10 MAP LOCATIONS: SPOT OGP-1246: pI=5.01; Mw=31502 SPOT OGP-1248: pI=4.63; Mw=31413 Cross-references UniProtKB/Swiss-Prot P67936; TPM4_HUMAN. 2D PAGE maps for identified proteins How to interpret a protein map You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw. Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly. Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed. External data extracted from UniProtKB/Swiss-Prot Extracted from UniProtKB/Swiss-Prot, release: 0.0 Entry name TPM4_HUMAN Primary accession number P67936 Secondary accession number(s) P07226 Q15659 Q5U0D9 Q9BU85 Q9H8Q3 Q9UCS1 Q9UCS2 Q9UCS3 Q9UCS4 Sequence was last modified on  January 23, 2007 (version 3) Annotations were last modified on  March 15, 2017 (version 136) Name and origin of the protein Description RecName: Full=Tropomyosin alpha-4 chain; AltName: Full=TM30p1; AltName: Full=Tropomyosin-4; Gene name Name=TPM4 Encoded on Name=TPM4 Keywords Acetylation; Actin-binding; Alternative splicing; Calcium; Coiled coil; Complete proteome; Cytoplasm; Cytoskeleton; Direct protein sequencing; Metal-binding; Muscle protein; Phosphoprotein; Polymorphism; Reference proteome. Copyright Copyrighted by the UniProt Consortium, see http://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License Cross-references EMBL X05276; CAA28888.1; -; mRNA EMBL AK023385; BAB14554.1; -; mRNA EMBL AK315076; BAG37545.1; -; mRNA EMBL BT019634; AAV38440.1; -; mRNA EMBL CH471106; EAW84521.1; -; Genomic_DNA EMBL BC002827; AAH02827.1; -; mRNA EMBL BC037576; AAH37576.1; -; mRNA EMBL BC067225; AAH67225.1; -; mRNA EMBL M12127; AAA36774.1; -; mRNA CCDS CCDS12338.1; -; . CCDS CCDS46007.1; -. [P67936-2]; . PIR S07282; S07282; . RefSeq NP_001138632.1; NM_001145160.1. [P67936-2]; . RefSeq NP_003281.1; NM_003290.2. [P67936-1]; . UniGene Hs.631618; -; . UniGene Hs.665133; -; . ProteinModelPortal P67936; -; . SMR P67936; -; . BioGrid 113024; 91; . IntAct P67936; 39; . MINT MINT-4138291; -; . iPTMnet P67936; -; . PhosphoSitePlus P67936; -; . SwissPalm P67936; -; . BioMuta TPM4; -; . DMDM 54039751; -; . DOSAC-COBS-2DPAGE P67936; -; . OGP P07226; -; . EPD P67936; -; . PeptideAtlas P67936; -; . PRIDE P67936; -; . DNASU 7171; -; . Ensembl ENST00000300933; ENSP00000300933; ENSG00000167460. [P67936-1]; . Ensembl ENST00000344824; ENSP00000345230; ENSG00000167460. [P67936-2]; . GeneID 7171; -; . KEGG hsa:7171; -; . UCSC uc002ndi.3; human; . CTD 7171; -; . DisGeNET 7171; -; . GeneCards TPM4; -; . H-InvDB HIX0022609; -; . HGNC HGNC:12013; TPM4; . HPA CAB004685; -; . HPA HPA047089; -; . HPA HPA053624; -; . MalaCards TPM4; -; . MIM 600317; gene; . neXtProt NX_P67936; -; . OpenTargets ENSG00000167460; -; . Orphanet 178342; Inflammatory myofibroblastic tumor; . PharmGKB PA36693; -; . GeneTree ENSGT00550000074494; -; . HOVERGEN HBG107404; -; . InParanoid P67936; -; . KO K10375; -; . OMA QMEDELM; -; . OrthoDB EOG091G0UO7; -; . PhylomeDB P67936; -; . TreeFam TF351519; -; . Reactome R-HSA-390522; Striated Muscle Contraction; . Reactome R-HSA-445355; Smooth Muscle Contraction; . ChiTaRS TPM4; human; . GeneWiki TPM4; -; . GenomeRNAi 7171; -; . PRO PR:P67936; -; . Proteomes UP000005640; Chromosome 19; . Bgee ENSG00000167460; -; . CleanEx HS_TPM4; -; . ExpressionAtlas P67936; baseline and differential; . Genevisible P67936; HS; . GO GO:0005884; C:actin filament; IBA:GO_Central; . GO GO:0030863; C:cortical cytoskeleton; IEA:Ensembl; . GO GO:0005856; C:cytoskeleton; TAS:UniProtKB; . GO GO:0005829; C:cytosol; TAS:Reactome; . GO GO:0070062; C:extracellular exosome; IDA:UniProtKB; . GO GO:0031941; C:filamentous actin; IEA:Ensembl; . GO GO:0005925; C:focal adhesion; IDA:UniProtKB; . GO GO:0016020; C:membrane; IDA:UniProtKB; . GO GO:0005862; C:muscle thin filament tropomyosin; TAS:ProtInc; . GO GO:0002102; C:podosome; IEA:Ensembl; . GO GO:0001725; C:stress fiber; IDA:MGI; . GO GO:0051015; F:actin filament binding; IBA:GO_Central; . GO GO:0005509; F:calcium ion binding; NAS:UniProtKB; . GO GO:0008307; F:structural constituent of muscle; TAS:ProtInc; . GO GO:0007015; P:actin filament organization; IBA:GO_Central; . GO GO:0006928; P:movement of cell or subcellular component; TAS:UniProtKB; . GO GO:0006936; P:muscle contraction; IBA:GO_Central; . GO GO:0030049; P:muscle filament sliding; TAS:Reactome; . GO GO:0001649; P:osteoblast differentiation; IDA:UniProtKB; . InterPro IPR000533; Tropomyosin; . Pfam PF00261; Tropomyosin; 1; . PRINTS PR00194; TROPOMYOSIN; . PROSITE PS00326; TROPOMYOSIN; 1; .

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• The World-2DPAGE Constellation - Entry point to the world-wide 2-DPAGE resources.
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• SWISS-2DPAGE - The Geneva Two-dimensional polyacrylamide gel electrophoresis database.
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